GRADE stands for ‘Grading of Recommendations Assessment, Development and Evaluation’. It was developed for health systems interventions. The GRADE approach separates two issues: 'the quality of the evidence and the strength of recommendations.
Grading instruments can help policy decision makers evaluate research on a given topic. There are many grading instruments available to “…provide a metric to ‘quantify’ the quality of evidence from either an individual study or from a body of evidence”.